One day, as Jesse James and his gang were riding through Missouri, they saw a farmhouse and stopped to ask for something to eat. A widow lived there with three small children. She didn't have much in the house, but shared with them what she had.

Way back in the deep woods there lived a scrawny old woman who had a reputation for being the best conjuring woman in the Ozarks. With her bedraggled black-and-gray hair, funny eyes - one yellow and one green - and her crooked nose, Old Betty was not a pretty picture, but she was the best there was at fixing what ailed a man, and that was all that counted.